Principal Clinical Scientist
Principal Clinical Scientist (AI Training)
About the Role
What if your career designing rigorous clinical trials and interpreting regulatory-grade data could directly influence how AI understands medicine? We're looking for a Principal Clinical Scientist to bring senior-level clinical expertise into the development of cutting-edge AI systems - helping ensure these models reason about clinical evidence the way a seasoned scientist would. This is a fully remote, flexible contract role built for experienced clinical researchers who want to work at the intersection of science and frontier AI. No AI background required - just deep clinical expertise and a sharp eye for scientific rigor. Organization : Alignerr Type : Hourly Contract Location : Remote Commitment : 10-40 hours/week
What You'll Do
Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards Evaluate AI-generated clinical analyses for scientific soundness and compliance with FDA, EMA, or equivalent agency expectations Provide expert feedback that directly shapes how AI models understand, reason about, and evaluate clinical trial data and outcomes Flag gaps in methodology, data quality, or regulatory relevance across AI-generated clinical content Who You Are Senior-level clinical researcher with hands-on experience designing trial protocols for regulatory submission Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies Strong grounding in clinical research methodology, biostatistics, or translational science Naturally rigorous - you hold AI-generated outputs to the same standard you'd apply in a real submission Self-directed and comfortable working independently in an asynchronous environment
Nice to Have
Prior experience with data annotation, data quality evaluation, or AI output assessment Background in pharmacology, oncology, rare disease, or another specialized therapeutic area Familiarity with ICH guidelines, GCP standards, or regulatory submission frameworks Experience working across multidisciplinary research teams
Why Join Us
Work directly on frontier AI systems that are reshaping how clinical and biomedical research is conducted Influence how AI understands and evaluates real-world clinical evidence - at a scale no individual trial could achieve Fully remote and flexible - work when and where it suits you Freelance autonomy with the structure of meaningful, high-impact, task-based work Collaborate with world-leading AI research labs on problems that matter Potential for ongoing work and contract extension as new projects launch Experience: 5 years required