Director / Senior Director, Medical Affairs

Position Summary REMOTE (located in EST) The Director / Senior Director, Medical Affairs will report to the Chief Medical Officer. The Director/Senior Director play a key role in shaping and executing Belenos’ medical and scientific strategy across its immunology pipeline, with an initial focus on BEL512. The successful candidate will serve as a scientific representative of Belenos to external medical experts, clinical investigators, and the broader scientific community. They will work closely with Clinical Development, Clinical Operations, Regulatory Affairs, and senior leadership to ensure that scientific insights from external experts inform clinical development strategy, evidence generation, and medical communications. This is a highly visible, hands-on position offering the opportunity to contribute directly to multiple clinical programs and help establish the Medical Affairs function within a growing biotechnology company. Key Responsibilities: Medical and Scientific Strategy Develop and execute medical affairs strategies aligned with Belenos’ clinical development priorities and long-term pipeline objectives. Provide scientific and medical expertise across immunology indications, particularly respiratory and type 2 inflammatory diseases, including CRSwNP, asthma, COPD, and atopic dermatitis. Maintain an in-depth understanding of disease biology, evolving treatment paradigms, unmet medical needs, and the competitive landscape. Evaluate emerging scientific and clinical data and translate findings into actionable recommendations for clinical development and medical strategy. Contribute to indication-specific scientific narratives and differentiated product profiles based on evolving clinical evidence. Support planning for future medical affairs capabilities as programs progress toward regulatory submission and potential commercialization. Key Opinion Leader and Investigator Engagement Work closely with Belenos’ established network of key opinion leaders (KOLs), academic investigators, and clinical experts to strengthen existing scientific relationships, while identifying and developing new KOL relationships where needed to support the company’s expanding clinical development programs. Lead and coordinate scientific advisory boards and expert consultations to obtain insights on clinical development strategy, trial design, endpoints, patient populations, and unmet medical needs. Represent Belenos in scientific discussions with external experts, academic institutions, patient advocacy groups, and professional societies. Gather and communicate external scientific insights to inform internal development decisions. Support engagement with investigators and clinical experts across the United States, Europe, Japan, and other relevant markets. Develop relationships with emerging clinical leaders and researchers who may become important collaborators in future Belenos programs. Clinical Development and Evidence Generation Partner closely with Clinical Development to provide medical and scientific input into clinical development plans, protocols, endpoints, exploratory analyses, and target product profile. Contribute to clinical trial strategy through engagement with investigators and external experts, including assessment of clinical relevance, feasibility, and unmet medical needs. Support interpretation and scientific communication of clinical efficacy, safety, pharmacodynamic, and biomarker results. Identify opportunities for additional analyses and evidence generation that may strengthen understanding of treatment effects, patient subgroups, and clinical differentiation. Support development of investigator-initiated research and external scientific collaborations, as appropriate. Assist with the scientific aspects of clinical investigator engagement and study-related communications. Scientific Communications and Publications Develop and implement publication and scientific communication strategies for Belenos’ clinical programs. Work with internal teams, external investigators, and publication partners to support preparation of manuscripts, congress abstracts, posters, and oral presentations. Ensure timely, accurate, and scientifically rigorous dissemination of clinical data. Develop and review scientific presentations, medical information materials, and educational content for appropriate external audiences. Coordinate scientific communication activities around major medical congresses in respiratory medicine, allergy, immunology, dermatology, and otolaryngology. Maintain awareness of competitor publications, clinical trial readouts, and emerging scientific developments relevant to Belenos’ pipeline. Ensure publications and scientific communications follow applicable ethical, regulatory, and industry standards. Cross-Functional Collaboration Serve as a key medical and scientific partner to Clinical Development, Clinical Operations, Regulatory Affairs, and executive leadership. Support preparation for scientific advisory boards, regulatory interactions, and other external expert engagements. Collaborate on development and review of scientifically accurate materials for corporate presentations and investor communications, as appropriate. Provide medical and scientific input into assessments of new indications, pipeline opportunities, and potential external collaborations. Help establish scalable Medical Affairs processes and external engagement practices appropriate for a clinical-stage biotechnology company.

Qualifications

Required: Advanced degree in a relevant scientific or medical discipline (MD, PhD, PharmD, or equivalent). For Director: typically 7+ years of relevant pharmaceutical or biotechnology industry experience; for Senior Director: typically 10+ years, with significant responsibility in Medical Affairs, Clinical Development, or related scientific functions. Strong scientific background in immunology, inflammatory diseases, or respiratory medicine. Demonstrated experience engaging with academic investigators, clinical experts, and KOLs. Experience interpreting clinical trial data and communicating complex scientific information to medical and scientific audiences. Experience supporting scientific publications, congress presentations, advisory boards, or other medical communication activities. Excellent communication, presentation, interpersonal, and relationship-building skills. Ability to work independently, prioritize effectively, and operate successfully in a fast-paced, resource-conscious biotechnology environment. Willingness to travel domestically and internationally as required. Preferred: Experience in asthma, CRSwNP, COPD, atopic dermatitis, allergy, or related immune-mediated diseases. Familiarity with type 2 inflammatory pathways, including TSLP, IL-13, IL-4, IL-33, and related mechanisms. Experience with biologic therapies, monoclonal antibodies, or bispecific antibodies. Prior Medical Affairs experience supporting Phase 2 and Phase 3 clinical development programs. Experience in a small or emerging biotechnology company, particularly establishing Medical Affairs activities before commercialization. Established scientific relationships with leaders in respiratory medicine, allergy/immunology, otolaryngology, or dermatology. Experience supporting global clinical programs and collaborating with international investigators. Familiarity with biomarker-driven clinical development and interpretation of translational medicine data. Personal Attributes: The ideal candidate combines scientific depth, strategic judgment, and the practical ability to execute in a growing biotechnology company. Scientifically rigorous: Critically assesses complex clinical and translational data and engages credibly with leading medical experts. Strategic and commercially aware: Understands how medical insights, clinical differentiation, and evidence generation contribute to drug development and future product positioning.