Remote Position

[Remote] Principal Software Engineer, AI-Native

๐ŸŒ Remote ยท United States ๐Ÿ’ผ Full-time

Note: The job is a remote job and is open to candidates in USA. RxSense is a healthcare technology company focused on pharmacy benefits. The Principal Software Engineer, AI-Native will architect and build production systems across the engineering stack, establish AI evaluation and monitoring infrastructure, and guide technical standards and architecture across teams.

Responsibilities

  • Architect and build production systems across a multi language stack: C#/.NET services, Python AI and data pipelines, and occasional TypeScript
  • Set the example for an AI forward, high technical standard across the broader engineering organization, leading through craft rather than organization wide authority
  • Design and drive adoption of offline evaluation frameworks (test suites, golden datasets, regression harnesses wired into CI/CD) for LLM based and other non deterministic components
  • Build online evaluation and monitoring that continuously assesses live model and system behavior in production, including drift and regression detection
  • Partner with engineering leadership to surface systemic risks in AI features, such as reliability, correctness, and drift, and drive the fixes
  • Lead architecture reviews for major initiatives and mentor senior and staff engineers on system design, evaluation methodology, and AI forward practices
  • Prototype and ship new AI capabilities

Skills

  • 8+ years of professional software engineering experience, with demonstrated Staff, Principal, or Architect-level scope โ€” e.g., owning system architecture end-to-end, driving technical strategy across multiple teams, or being accountable for critical production systems
  • Strong candidates with less tenure but clear evidence of this level of ownership are encouraged to apply
  • Depth across backend and AI/ML systems, working in some combination of C#/.NET, Python, and TypeScript
  • Experience with LLM observability, prompt and response evaluation, or agentic system testing
  • A track record of setting technical standards that other engineers and teams adopt
  • Strong communication skills, with the ability to align engineers and leadership around a shared technical direction
  • Comfort working in an AI forward engineering environment, for example with agentic coding tools such as Claude Code
  • Equivalent practical experience will be considered in lieu of a formal degree
  • Bachelor's degree in Computer Science, Engineering, or a related field preferred
  • Experience in pharmacy benefits, healthcare, fintech, or another regulated, high stakes domain
  • Familiarity with distributed systems tooling such as Kafka, gRPC, Grafana, and Dragonfly / Redis
  • A good eye for clean, usable interfaces for the occasional front end work

Benefits

  • First-class tools for the work ahead, with engineers building using modern agentic tooling standardized on Anthropic's Claude.

Company Overview

  • RxSense is a health technology company provides IT solutions for flexible, efficient, and transparent pharmacy benefits administration. It was founded in 2015, and is headquartered in Boston, Massachusetts, USA, with a workforce of 201-500 employees. Its website is https://rxsense.com/.
  • Company H1B Sponsorship

  • RxSense has a track record of offering H1B sponsorships, with 2 in 2026, 2 in 2025, 3 in 2024, 4 in 2023, 1 in 2022, 5 in 2021, 10 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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